The associated pathways included innate immune response (cytotoxicity of natural killer cells, endotoxin-stimulated MAPK, mTOR, and HIF-1), adaptive immune response (T cell receptor signaling, B cell receptor signaling, and Th1/Th2 differentiation), endothelial dysfunction (VEGF pathway and apoptosis), and endocrine resistance to sepsis. Here, VEGFA is linked to Sepsis.