DSG1 and pemphigus: In addition, frequencies of Th17 and Tfh17 cells in the blood of patients with pemphigus correlate with levels of Dsg-specific CD19+CD27+ memory B cells (Maho-Vaillant et al., 2021), while patients with acute pemphigus exhibit higher levels of Dsg3-autoreactive Tfh17 cells (Hennerici et al., 2016).