Therefore, NRS2002 nutritional screening, PG-SGA nutritional assessment and other nutrition-related indicators (weight, grip strength, upper arm circumference, serum hemoglobin, albumin, prealbumin, and total protein) should be dynamically monitored in patients with GIST during perioperative period, and necessary nutritional support should be given to patients with malnutrition. The gene discussed is TTR; the disease is gastrointestinal stromal tumor.