We were interested in understanding how the expression of 3′-UTR and CDS of Ckip-1 mRNA were altered during cardiac atrophy, since we previously reported Ckip-1 was a striking gene within the incongruous expression of mRNA 3′-UTR and CDS after heart failure (Zhao et al., 2021). The gene discussed is PLEKHO1; the disease is Atrophy.