SNPH and neoplasm: Lowering of syntaphilin (SNPH), a neuronal cytoskeletal protein that regulates mitochondrial movement causes relocalization of mitochondria from perinuclear position to the cortical cytoskeleton and leads to increased tumor cell motility (Caino et al., 2016; Caino et al., 2017; Seo et al., 2018) (Figure 3A).