In recent years, it has been found that DUXAP10 is excessively expressed in pancreatic (Lian et al., 2018) cancer (PC) tissues and cell lines (AsPC-1, BxPC-3, and PANC-1 cells), and a close correlation was observed between the overexpression of DUXAP10 and unfavorable clinicopathological characteristics, such as poor prognosis, aggressive TNM stage and lymph node metastasis. The gene discussed is DUXAP10; the disease is pachyonychia congenita.