DUXAP10 and lung cancer: Moreover, in vitro functional assays and in vivo tumor models have demonstrated that DUXAP10 is mainly implicated in eliciting the transformation of Cd-exposed (Cd-T) cells to cancer stem cells (CSCs), promoting the cell cycle progression, proliferation, migration, and invasion of A549 or H1975 cells, and thus accelerating tumorigenesis and progression in lung cancer.