In CRC (Lian et al., 2017), DUXAP10 regulates the expression of p21 and phosphatase and tensin homolog (PTEN) by binding to the histone demethylase lysine-specific demethylase 1 (LSD1), enhancing CRC cell proliferation and reducing apoptosis. The gene discussed is DUXAP10; the disease is colorectal carcinoma.