Consequently, to ensure that we capture all the relevant transcriptomic changes resulting from the loss of Abcc6, we used a cutoff of p ≤ 0.01 with a fold change of ≥1.75 resulting in a list of 144 DEGs in Abcc6−/− AF tissue (Figure 6B). The gene discussed is ABCC6; the disease is atrial fibrillation.