CCL2 and breast carcinoma: In rats inoculated with breast carcinoma cell Walker-256, Wang et al. found a significant increase in monocyte chemoattractant protein-1 (MCP-1)/chemokine CC motif receptor-2 (CCR2) and NF-κB expression in spinal cord neurons, but this effect was inhibited by treatment with BAY 11-7082 (Wang et al., 2018).