S100P and lip and oral cavity carcinoma: It is worth mentioning that saliva contains many biomarkers, such as SA (Hernández-Cedillo et al., 2019) and carotenoids (Kim et al., 2010; Gonchukov et al., 2011) for periodontitis diagnosis, and thiocyanate (Falamas et al; Fălămaş et al., 2020) and S100P mRNA (Han et al., 2019) for oral cancer detection.