CD4 and cancer: The immune infiltrates scores based on CIBERSORT, XCELL, TIMER and MCPCOUNTER algorithms were retrieved from TIMER 2.0 database (http://timer.cistrome.org/) indicated the comparison of the infiltrated immune cell levels between the high- and low-risk groups (Figure 6A), which shown the significant immune cell type proportions based on various algorithms, revealed that cancer associated fibroblast, CD4+ Th2 cells, M1 macrophages were upregulated in the high-risk group.