For example, the circRNA hsa_circ_0072088, miRNAs (hsa-miR-532-3p and hsa-miR-942-5p), and mRNAs (IGF2BP3, MKI67, CD79A, and ABAT) may serve as prognostic markers in LUAD via a circRNA-mediated ceRNA network (18); LINC00324/miR-9-5p (miR-33b-5p)/GAB3 (IKZF1) may play a pivotal role in regulating TAM risk and prognosis in LUAD patients (19), and some studies focus on cancer-related lncRNAs to search crucial RNA interactions based on ceRNA networks (20, 21). This evidence concerns the gene MKI67 and cancer.