The pancancer analysis showed abnormally increased YTHDF2 expression in many tumour tissue types, such as head and neck squamous cell carcinoma, bladder urothelial carcinoma, cervical squamous cell carcinoma, cholangiocarcinoma, oesophageal carcinoma, stomach adenocarcinoma and lung squamous cell carcinoma, in TCGA database (Figure 1I). This evidence concerns the gene YTHDF2 and head and neck squamous cell carcinoma.