PRTN3 and Skin rash: Systemic manifestations were noted in 50% of the patients; five (41.6%) patients had a skin rash and one (8.3%) patient had uveitis. Among 10 patients with AAV, six patients were positive for C-ANCA and PR3 whereas three patients were positive for P-ANCA and MPO. GPS was confirmed with serum anti-glomerular basement membrane (anti-GBM) antibodies with clinical presentation.