TSHR and thyrotoxicosis: Thyrotoxicosis can also manifest with organ decompensation leading to multisystem organ failure, commonly including the heart, lungs, liver, and kidneys [6]. While thyrotropin receptor antibodies, radioactive iodine scintigraphy, or thyroid blood flow via ultrasonography can all be used to diagnose thyrotoxicosis, the diagnostic accuracy improves when thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) are also evaluated [7,8].