RIPK4 and familial pancreatic carcinoma: RIPK4 expression is up-regulated and relates with a poor prognosis in ovarian cancer, cervical SCC, pancreatic cancer, bladder cancer and osteosarcoma (Qi et al., 2018; Liu et al., 2015; Liu et al., 2018; Yi et al., 2020; Liu et al., 2021).