RIPK4 can function as an independent prognostic indicator of worse outcome in colon adenocarcinoma (COAD) and in ovarian serous cystadenocarcinoma (OV) while RIPK4 overexpression predicts better outcome in kidney renal papillary cell carcinoma (KIRP) and kidney renal clear cell carcinoma (KIRC) (Fig. 5). Here, RIPK4 is linked to colon adenocarcinoma.