Recently, dysregulation of various lncRNAs, such as MIR100HG, BANCR, H19, CASC15, MALAT1, TUSC7, MEG3, and HOTAIR in apoptosis, cell proliferation, migration, metastasis, invasion, and tumorigenicity of GC has been reported by different studies [6–11]. This evidence concerns the gene HOTAIR and gastric cancer.