Zhao et al. reported that PD treatment (7.5, 15, and 30 mg/kg) for 11 weeks antagonized the nuclear translocation of the Zinc finger E-box binding homeobox 1 (ZEB1) and inhibit survivin-activated TGF-β1/Smad signaling, which was consistent with its protective effect on fructose-induced EMT and liver fibrosis. The gene discussed is TGFB1; the disease is Hepatic fibrosis.