Besides, PD abrogated slight liver steatosis, increased carnitine palmitoyl transferase-1 (CPT-1) and peroxisome proliferator-activated receptor-α (PPAR-α) protein levels, decreased stearoyl-CoA desaturase-1 (SCD-1) and sterol regulatory element binding protein 1 (SREBP-1) protein levels, and reduced total cholesterol (TC) and TG levels in the fructose-fed liver of rats [56]. This evidence concerns the gene SREBF1 and fatty liver disease.