There was a slight increase in E-cad protein levels in KCs treated with the MC-CM/shPmel17 compared to the scramble control, and no change in the F-actin pattern was discerned in KCs treated with the MC-CM/shPmel17 compared to those treated with MC-CM, even after exposure to UVB (Figure 4(c)). This evidence concerns the gene CDH1 and dry eye syndrome.