Next, she was hospitalized due to uncontrolled hyperglycemia and upper respiratory tract infection for 48h, and empirically received broad-spectrum antibiotic meropenem, 1 g iv., twice a day (b.i.d.)for intensive monitoring of the concomitant septicemia and insulin glargine (Lantus®) and insulin aspart (Novorapid®), as well as a fixed-dose combination antidiabetic medication (empagliflozin/metformin hydrochloride, 5/1000 mg, orally), were also applied for blood glucose adjustment. This evidence concerns the gene INS and Recurrent upper respiratory tract infections.