The main pathways of Danlong Dingchuan Decoction effects on asthma were as follows: cAMP signaling pathway (fold enrichment = 4.25), cGMP-PKG signaling pathway (fold enrichment = 4.74), NF-κB signaling pathway (fold enrichment = 5.92), and PI3K-Akt signaling pathway (fold enrichment = 2.17), which were associated with MAPK3, TLR4, TNF, and other similar proteins (Figure 5). Here, TLR4 is linked to asthma.