WAS and cancer: In humans, PAK and WASP family proteins have been thoroughly inspected, both functionally and biochemically, and they proved to be potential targets against cancer, neurodegenerative and cardiovascular diseases (Kichina et al., 2010; Li et al., 2010; Zhao and Manser, 2010; Llorens et al., 2013; Dammann et al., 2018).