LRRC4 and posterior cortical atrophy: In our study, LRRC4 was mainly associated with the WNT signaling pathway, the MAPK signaling pathway, and oxidative phosphorylation, which are the common pathways in the progression of PCA (Schöpf et al., 2016; Murillo-Garzón and Kypta, 2017; Park et al., 2020).