According to previous studies, the mechanisms of albinism in flatfish can be ascribed to mutations in tyrosine metabolism-related genes (e.g., tyr and tyrp1), which have also been verified in other fishes and mammals (Arshad et al., 2018; Chi et al., 2006; Fistarol and Itin, 2010; Beirl et al., 2014; Klaassen et al., 2018; Pavan and Sturm, 2019; Jeong et al., 2020). This evidence concerns the gene TYR and albinism.