Figure 8G depicts the heterogeneity in clinical phenotypes including age, T, N, M, stage, and known breast cancer subtypes among the five clusters. Considering the known breast cancer subtypes, we compared the five TSG-based subtypes with known breast cancer subtypes (Basal, Her2, LumA, and LumB). Our results showed that specific TSG-based subtypes had a high coincidence rate with known subtypes (Figure 8H). This evidence concerns the gene TMEM43 and breast carcinoma.