According to the GO and KEGG analysis for the DEGs (Table S4) between patients with IPF and controls in the monocytes with S100A12 >0, monocytes with S100A12 >0 of patients with IPF might be more associated with antigen processing and presentation (Figure 8E and Supplementary Figure 14E). The gene discussed is S100A12; the disease is idiopathic pulmonary fibrosis.