immunoglobulin G1 (IGHG1), nephronectin (NPNT), and methyl-CpG-binding domain protein 1 (MBD1) were significantly increased in the OCGB positive patients relative to OCGB negative (irrespective of MS diagnosis) while IgG-receptor (FCGR1A) was decreased. This evidence concerns the gene IGHG1 and myeloid sarcoma.