FKBP5 and Anxiety: As shown in Table 3, among the 26 CpG units in the promoter region of the FKBP5 gene detected in our study, the DNA methylation level at FKBP5-12 CpG 15 (β = −0.263, P < 0.05) was associated with an increased risk of anxiety symptoms after adjusting for age, gender, BMI, living arrangement, HSS, academic pressure, classmate relationships, teacher-classmate relationships, current drinking, and anxiety symptoms at baseline.