SLC5A2 and type 2 diabetes mellitus: One of the four SGLT2 inhibitors approved by the US Food and Drug Administration (FDA) is empagliflozin that, both in patients with or without T2DM, has demonstrated to have additional renoprotective and cardioprotective effects that are independent of the glycaemic control (Zinman et al., 2015; Täger et al., 2020).