HMOX1 and allergic asthma: In ovalbumin-induced allergic asthma model, Wu et al. illustrated that intraperitoneal administrated with alpinetin (25–100 mg/kg) showed remarkable anti-inflammatory function, and the molecular mechanism was associated with disorganizing PI3K/Akt/NF-κB and activating HO-1 pathways (Wu et al., 2020).