IL6 and COVID-19: Severe COVID-19 patients commonly exhibit a hyperinflammatory state referred to as cytokine storm, marked by elevation of IL-2, IL-4, IL-6, TNF-α, and IFN-γ (Copaescu et al., 2020; Hu et al., 2021; Paniri and Akhavan_Niaki, 2020; Qin et al., 2020; Zhang et al., 2021a).