IL1B and COVID-19: Among them, IL-6, IL-1β, CXCL8, CCL2, IL-2, IL-4, ICAM1, IL-10, IFNG, and IL-1A are seen as important targets of JHQG for treating COVID-19 (Lin et al., 2020), and all of them are related to immune regulation (Chen et al., 2019).