Another study predicted 52 potential targets of XBJ for treating COVID-19, including IL-6, TNF, TP53, CASP3, IL-10, MAPK8, MAPK1, LI1B, CCL2, IL-4, etc., and it is thought to be involved in immune responses (Dai et al., 2020). This evidence concerns the gene MAPK8 and COVID-19.