NPY and Spinocerebellar ataxia type 3: Given the neuroprotective role of NPY and its receptors in neurodegenerative disease (Decressac and Barker, 2012; Decressac et al., 2012; Geloso et al., 2015), exploring other functional SNPs or the whole exons of these genes in MJD patients is suggested before a definite conclusion is reached.