Unexpectedly, miR-155 activity protected mice against early paraplegia, for increasing miR-155 activity in ChAT+ neurons (MN-miR-155-KI mice) reduced the percentage of paraplegia at 24-h post-ACC by three times as compared with either control mice (Chi-square: p = 0.0342; Fisher exact test: p = 0.0426) or MN-miR-155-KO mice (Chi-square: p = 0.0516; Fisher exact test: p = 0.0855) (Figures 1C,D and Table 1). Here, CHAT is linked to paraplegia.