The above results indicate that: (i) there is no direct correlation between either the pattern of edema or the average volume of edema with the percentage of paraplegia at 48-h post-ACC; and (ii) the development and anterior spreading of central cord edema is more likely caused by the inflammation that develops during the second day post-ACC, and whose level is primarily determined by miR-155 expression in ChAT+ neurons. The gene discussed is CHAT; the disease is paraplegia.