Most forms of hemochromatosis cause injury in peripheral tissues (heart and liver), however, it should be noted that the principal variants of the HFE gene can affect brain iron homeostasis and is considered as a risk factor for neurodegenerative disorders, particularly Parkinson’s disease (Dekker et al., 2003; Guerreiro et al., 2006). This evidence concerns the gene HFE and hemochromatosis.