SHBG and polycystic ovary syndrome: Women in the OW-PCOS subgroup exhibited significantly attenuated insulin sensitivity and enhanced androgen production, such as increased 60 min and 120 min insulin levels of the OGTT (66.24% and 2.01-fold, respectively), decreased SHBG, and elevated FAI, compared to women in the NW-PCOS subgroup (P < 0.001 or P < 0.01, Supplementary Table 1).