In order to further explore the roles of lncRNA RGMB-AS1 and FOXA1 in NPC development for elucidating the potential mechanism of lncRNA RGMB-AS1 on NPC, here, we firstly focused on the expressions of lncRNA RGMB-AS1, FOXA1 and EMT-related markers in nasopharyngeal carcinoma and their related clinical significance. This evidence concerns the gene FOXA1 and nasopharyngeal carcinoma.