TP53 and cancer: Multiple cancer hallmark pathways such as GC network, transcriptional regulation by TP53, and cell population proliferation were enriched in subclone 0 (Figure S5D), whereas antigen processing and presentation, cellular response to topologically incorrect protein, and hormone‐mediated signalling pathway were activated in subclone 2 (Figure S5E), showing the intra‐tumoural heterogeneity in the primary tumour PT2.