In N3 cells, IPA revealed that the pathways of iNOS signalling, IL‐6 signalling, and oxidative phosphorylation were activated (Figure S16D), whereas migration of tumour cell lines and epithelial–mesenchymal transition were positively regulated, and the phagocytosis of cells and cytotoxicity of lymphocytes were inhibited (Figure S16D and E). The gene discussed is NOS2; the disease is neoplasm.