Consistently, a previous study showed that epithelial cancer cells, as well as tumour DCs and macrophages, contributed to HLA‐E enrichment in adenocarcinoma including esophageal, colorectal, lung, and kidney cancer, and this enrichment related to KLRC1 upregulation on tumour‐infiltrating CD8+ T lymphocytes.111. This evidence concerns the gene HLA-E and adenocarcinoma.