More interestingly, the KEGG analysis from cluster 2 also demonstrated that inflammation‐related pathways, such as Cytokine‐cytokine receptor interaction, Chemokine signalling pathway, TNF signalling pathway, Jak‐STAT signalling pathway, IBD, Toll‐like receptor signalling pathway and NF‐kappa B signalling pathway, were significantly enriched. The gene discussed is TNF; the disease is inflammatory bowel disease.