Further mechanistic studies uncovered that CTCF‐transcribed long noncoding RNA (LncRNA) prostaglandin‐endoperoxide synthase 2 (PTGS2) antisense NF‐κB1 complex‐mediated expression regulator RNA (PACERR) participates in cis‐regulation of the expression of PTGS2 (also known as COX‐2), a key driver of pro‐tumour TAMs. This evidence concerns the gene CTCF and neoplasm.