Considering that SMCs are the major cell type that undergoes phenotypic transformation during the vascular calcification process,34 and that OMD protein was localised within α‐SMA+ areas in calcified tissues, we next utilised public scRNA sequencing data of human coronary and carotid atherosclerotic plaques to investigate the association of OMD with the various ACTA2+ plaque cell subtypes.35, 36. The gene discussed is ACTA2; the disease is occult macular dystrophy.