We also found a negative correlation of tissue OMD with pro‐calcifying DMP1 and IBSP glycoproteins, but positive with sclerostin (SOST, as in plasma from CKD patients) and osteonectin (SPARC) that presents strong binding affinity for type I collagen and hydroxyapatite,60 similarly as previously reported for OMD.61 This evidence concerns the gene IBSP and occult macular dystrophy.