CHML and non-small cell lung carcinoma: To determine if NRF2 regulates CHML/Rep2 levels in lung cells, NRF2 was either genetically or pharmacologically manipulated in BEAS‐2B (normal lung epithelial cell), H1299 (NSCLC) or A549 (NSCLC) cells and Rep2 protein levels were assessed (Fig. 1D‐H).