CCL2 and melanoma: Recently, KLAK-MCP-1 micelles containing a CCR2-targeting peptide sequence and apoptotic KLAK peptide to induce apoptosis were synthesized to interrupt the MCP-1/CCR2 axis, which successfully inhibited tumor growth in B16F10 melanoma by inhibiting the infiltration of TAMs into the tumor and elevating cytotoxic T lymphocytes [128].