HDGFL2 and malaria: Malaria RDT kits are predominantly based on the detection of P. falciparum histidine-rich protein (HRP2) and/or Plasmodium lactate dehydrogenase (LDH) antigens, and despite RDT kits having a similar sensitivity to microscopy [14–16], their ease of use and fast turnaround time have made them a preferred diagnostic tool [17, 18].