It is noteworthy that 11 of these variants were exclusive to tumours (somatic) in the study by [6] and distributed in four regions: D-loop (73, 489, 16093, 16189 and 16360), MT-ND1 (3594 and 3666), MT-ND4 (10810 and 10873), and MT-ND5 (13650 and 13789). Here, MT-ND4 is linked to neoplasm.