In patients with suspected hereditary ataxia, we identified expansions in loci that had not been assessed as part of routine diagnostic workup within the NHS at the time of recruitment, including ATN1, ATXN2, ATXN3, ATXN7, CACNA1A, FXN, TBP, and HTT (table 3). The gene discussed is TBP; the disease is Rare hereditary ataxia.