Furthermore, histological examinations showed that levels of YAP, GSR, and GCLC proteins were concomitantly elevated in Py8119 tumor tissues from obese mice, compared to those in lean mice (Figure 5G), but increased expressions of YAP, GSR, and GCLC were reduced by YAP‐knockdown (Figure 5G). This evidence concerns the gene GCLC and neoplasm.