SCAI and hypertensive disorder: However, among 100 INS patients, 18 had hypertension (7 maintained on captopril, 6 on losartan, and 5 combined captopril and nifedipine) the genotypes and alleles distribution in hypertensive compared to non-hypertensive patients did not show significant difference except for A2A2 genotype of ScaI polymorphism which was more frequent in hypertensive patients [p= 0.003], and A1 allele which was less frequent in hypertensive compared to non-hypertensive patients [p=0.012) (Table 3).