HOXA-AS2 and central nervous system cancer: Consistent with the clinical data, lncRNA HOXA-AS2 expression was high in glioma cell lines U373-MAGI, LN229, A172, and T98 compared to the normal glial Heb cell line, of which, LN229 and A172 cell lines exhibited the highest expression of lncRNA HOXA-AS2 (Fig. 1E) and were therefore selected for subsequent experimentations.