Correlating patient’s clinical data to local deep bisulfite sequencing results showed that none of the CpGs in MGMTe1 and MGMTi1 was predictive for the duration of a progression-free survival in our sample cohort of primary glioblastoma without IDH mutations and treatment with radiotherapy and concomitant chemotherapy with temozolomide. Here, IDH1 is linked to glioblastoma.