CNKSR1 and lung adenocarcinoma: In a previous study, Namani et al. have found that not only AOX1 serves as an NRF2 binding site, but Cnksr1, Peli2, and Svep1 also are highly correlated with the NRF2 pathway upregulation observed among the Keap1-mutated Lung adenocarcinoma patients [104].