In this regard, concerning Ccr7, the relationships between this chemokine receptor expression in lymph node and tumour cells metastasis were represented in various types of cancers such as colorectal [82], gastric [83], esophageal [84], hepatocellular [85], thyroid cancer [86], malignant melanoma [87], breast cancer [88], cervical cancer [89], and pancreatic cancer [90]. This evidence concerns the gene CCR7 and thyroid cancer.